An individual who achieved their weight loss goal.

Did you know that in 2022, 43% of adults aged 18 years and over were overweight? Furthermore, 16% were living with obesity. These figures represent a global concern about weight-related issues, and the prevalence of these statistics underscores the surge in individuals seeking practical solutions to address their weight concerns.

Obesity and overweight have become common concerns among adults and adolescents. Various solutions have surfaced, but Saxenda stands out for its proven safety and effectiveness in weight loss management in adults and teens. This is achieved through a carefully tailored plan with the correct dosage and treatment schedule.

This article will explore the Saxenda schedule, the recommended dosage and treatment plan, the duration of treatment, potential side effects, and considerations for discontinuing treatment.

Key Takeaways

  • The Saxenda dosing schedule is designed to minimize gastrointestinal side effects and help the patient’s body adjust to the medication.
  • Saxenda is usually recommended for a year but is generally safe and effective for extended use.
  • Many factors may affect the discontinuation of the treatment, including achieving weight loss goals, financial constraints, and patient tolerability.
  • Medical professionals should equip individuals with comprehensive information about the treatment, such as benefits, patient selection criteria, potential side effects, and how to recognize and manage them.
  • Saxenda’s safety and efficacy have undergone various clinical research and trials, providing valuable insights into its effectiveness and safety profile.

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Initial Dosing Schedule and Titration Steps

An individual administering an injection into their upper thigh.

Saxenda is a prescription injectable medicine to aid in weight loss management of obese or overweight adults and adolescents. For individuals starting this long-term treatment, it’s essential to understand the Saxenda schedule and its dosing. The Saxenda dosing schedule is designed to minimize gastrointestinal side effects and help the patient’s body adjust to the medication.

  • Recommended Starting Dose: The initial recommended dose of Saxenda is 0.6 mg daily for the first week. Moreover, Saxenda requires daily subcutaneous injections in the abdomen, thigh, or upper arm at any time of the day.
  • Titration Schedule: To achieve optimal outcomes, patients must reach the maintenance Saxenda dosage of 3 mg. After the initial week’s 0.6 mg dose, patients must increase by 0.6 mg weekly until they achieve the maintenance dose of 3 mg.

Gradual dose escalation is essential for individuals starting a new medication, allowing the body to adjust to the drug. Furthermore, this also reduces the risks of side effects and can optimize the effectiveness of Saxenda injections.

Duration of Treatment and Patient Response

Medical professionals may typically recommend Saxenda as a long-term treatment. The effectiveness of the injectable treatment requires evaluation after four months. The duration of Saxenda treatment may depend on the healthcare provider’s prescription, the patient’s needs, and health.

Saxenda is usually recommended for a year but is generally safe and effective for extended use. Regular follow-ups with medical professionals are crucial for monitoring patient response and progress during treatment. Moreover, providers may also ask patients to monitor other parameters relevant to their health.

These appointments may allow providers to make necessary dosage changes and a Saxenda schedule based on the patient’s weight loss progress and tolerability. If a patient cannot tolerate the 3 mg dosage, providers may suggest Saxenda alternatives, like Wegovy or Ozempic, for weight loss.

Considerations for Discontinuing Treatment

A doctor-patient consultation regarding weight loss management.

Saxenda stopping and restarting must be done under medical supervision. Many factors may affect the discontinuation of the treatment, including achieving weight loss goals, financial constraints, and patient tolerability. Other influences that can affect the decision include:

  • Duration of Treatment
  • Current Dose
  • Side Effects
  • Treatment Effectiveness
  • Patient Health

For individuals planning to discontinue the injectable medication, it’s essential to seek a medical practitioner’s guidance. Tapering off Saxenda involves a gradual reduction of the dosage. Like how the initial dosage increased weekly, a general guideline requires the 3 mg dosage to decrease by 0.6 mg weekly until reaching 0 mg.

However, it’s worth understanding that individuals stopping Saxenda have a potential rebound weight gain after discontinuation. This may result from the increased calorie consumption without the appetite regulation effects of the injection medication.

Practical Guidelines for Monitoring and Managing Side Effects

Like other medical or aesthetic treatments, Saxenda’s ingredients and the injectable may cause several side effects to individuals. These typical symptoms may temporarily resolve in a few days or weeks. Medical professionals’ proper prescription and adherence to the dosage can manage these side effects.

If these persist, patients must seek immediate medical attention. According to the Saxenda Prescribing Information, the most common reported adverse events that occur after treatment include:

  • Nausea
  • Diarrhea
  • Constipation
  • Vomiting
  • Injection site reactions
  • Headache
  • Hypoglycemia
  • Dyspepsia
  • Fatigue
  • Dizziness
  • Abdominal pain
  • Increased lipase
  • Upper abdominal pain
  • Pyrexia
  • Gastroenteritis

Other side effects management may involve proper balanced diet and lifestyle adjustments. Regular monitoring of vital signs and health parameters can help detect changes in the patient’s physiological status and allow providers to adjust the treatment plan.

Medical professionals should equip individuals with comprehensive information about the treatment, such as benefits, patient selection criteria, potential side effects, and how to recognize and manage them. Patient education allows these individuals to make informed decisions for their treatment and immediately report occurrences of adverse events.

References to Clinical Studies and Expert Recommendations

A medical professional preparing the prescription for patients.

Saxenda’s safety and efficacy have undergone various clinical research and trials, providing valuable insights into its effectiveness and safety profile. Many have highlighted its potency in addressing weight loss management in obese or overweight individuals and Saxenda for PCOS patients.

Clinical trials demonstrated that most adult patients achieved a ≥5% weight loss with Saxenda. A one-year study in adults revealed that 85% of Saxenda-treated patients with consistent reduced-calorie diets and physical activity led to clinically meaningful weight loss.

Moreover, a systematic review emphasizes liraglutide’s ability to induce and sustain weight loss in obese patients. While its efficacy is comparable to that of other weight loss management agents, studies found that liraglutide offers the benefit of improved glycemic control.

Optimizing Saxenda treatment requires strict adherence to the expert recommendations regarding the dosage and lifestyle modifications. Experts highly encourage starting with a low dose of Saxenda and gradually increasing it, minimizing potential side effects and preparing the body to adjust to the medication.

According to Saxenda, patients can maximize the weight loss efficacy of the prescription injectable if they combine it with a reduced-calorie diet and increased physical activity or regular exercise. Moreover, maintaining healthy daily habits, such as staying hydrated and avoiding vices, can also help sustain weight loss. 

Conclusion

Medical practitioners design the Saxenda schedule, dosing, and treatment plan to optimize patient outcomes. They carefully plan the initial dosing schedule and titration steps to minimize side effects and help patients adjust to the medication. Regular follow-ups monitor patient progress, side effects, and duration of treatment and make necessary adjustments.

Discontinuing treatment is based on several factors, including the patient’s response and tolerability. Patients can manage side effects through diet and lifestyle adjustments and are educated on recognizing and reporting adverse events. Numerous clinical studies have validated Saxenda’s effectiveness and safety, and expert recommendations are available to guide healthcare providers in optimizing treatment.

FAQs

The initial recommended dose of Saxenda is 0.6 mg daily for the first week to reach a maintenance dose of 3 mg.

Saxenda is typically recommended as a long-term treatment. It is generally safe and effective for extended use, but regular follow-ups with medical professionals are crucial.

3. What are the considerations for discontinuing Saxenda treatment?

Discontinuation factors include achieving weight loss goals, financial constraints, patient tolerability, duration of treatment, current dose, side effects, treatment effectiveness, and overall patient health. Discontinuation should be done under medical supervision and involve a gradual dosage reduction.

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References

  1. World Health Organization. (2024, March 1). Obesity and overweight. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
  2. Mehta, A., Marso, S. P., & Neeland, I. J. (2017). Liraglutide for weight management: a critical review of the evidence. Obesity science & practice, 3(1), 3–14. https://doi.org/10.1002/osp4.84