A medical syringe with several medical solution vials.

According to Papakonstantinou et al. (2012), intrinsic aging significantly impacts the skin’s aging process by decreasing hyaluronic acid (HA) content. Given HA’s crucial role in maintaining skin moisture, this research highlights the substance’s potential for therapeutic strategies to combat skin aging effects.

HA dermal fillers have gained popularity as a non-surgical option to address various skin concerns. In particular, Profhilo injections boast their unique HA formulation that delivers longer-lasting effects and results from within the skin’s deep layers. 

This article will delve into Profhilo ingredients, the composition of its hyaluronic acid, its bio-remodeling properties, and the injectable’s efficacy.

Key Takeaways

  • Profhilo injections are innovative, minimally invasive procedures that capitalize on hyaluronic acid’s potency to improve skin quality, texture, and elasticity from within.
  • Hyaluronic acid (HA) is a gooey, slippery substance naturally produced in the body.
  • Profhilo stimulates collagen and elastin production, improving skin quality and rejuvenation.
  •  A study article by Goltsova & Shemonaeva (2019) showed significant improvement in skin hydration and elasticity after treatment. 
  • Medical professionals with comprehensive knowledge about the treatment, facial anatomy, and proper Profhilo injection depth and technique can lead to optimal outcomes.

About: Medica Depot is your trusted all-in-one supplier, offering a range of high-quality medical injectables and supplies. Buy Profhilo wholesale at Medica Depot today! Whether for health professionals, plastic surgeons, dermatologists, licensed estheticians, or other specialists, we can offer genuine, brand-name products you may need. With Medica Depot, we prioritize serving you better to improve the patient’s quality of life.

The Role of Hyaluronic Acid in Profhilo

A close-up shot of hyaluronic acid solution.

Hyaluronic acid (HA) is a naturally occurring substance in the body, especially in the skin. It is known for its ability to retain water, ensuring tissues remain well-lubricated and moist. In skincare, HA hydrates and rejuvenates the skin. Moreover, dermal fillers utilize this substance to volumize and contour facial regions with their different HA formulation.

In particular, Profhilo injections are innovative, minimally invasive procedures that capitalize on hyaluronic acid’s potency to improve skin quality, texture, and elasticity from within. Thanks to its NAHYCO technology, it presents a unique HA gel substance that offers prolonged stimulating activity on the dermal cells.

Compared to other dermal fillers, Profhilo injections contain one of the highest HA concentrations in their injectables on the market. It also stands out due to its unique composition of pure HA, providing lasting hydration. Profhilo injections stimulate collagen and elastin production, deeply restructuring the skin and counteracting skin laxities.

The Properties of Hyaluronic Acid

The list of hyaluronic acid properties with a medical syringe and vial on the side.

Hyaluronic acid (HA) is a gooey, slippery substance naturally produced in the body. It’s proven safe for the body as it can be found in the eyes, joints, and skin. HA has remarkable skincare and medical care benefits: it helps joints work smoothly, retains water excellently, and aids skin flexibility.

  • HA’s Ability to Retain Moisture and Improve Skin Hydration: HA is a potent humectant capable of binding over a thousand times its weight in water. This property enhances skin hydration, promoting a revitalized and fresher look. Due to its unique capacity to retain water, medical professionals mainly use HA in skincare products.
  • HA’s Contribution to Skin Elasticity and Firmness: HA ensures skin’s viscoelasticity and firmness. It forms a dense, gelatinous mass in the dermis, enveloping fibers and cells, making it essential for smoother, healthier skin.

The Bio-Remodeling Effects of Profhilo

What sets Profhilo injections apart from other dermal fillers is their bio-remodeling effects. Instead of immediate volumizing and contouring like other hyaluronic acid (HA) fillers, Profhilo stimulates collagen and elastin production, improving skin quality and rejuvenation.

As a bio-remodeling agent, HA in Profhilo enhances skin texture and reduces the signs of aging. Profhilo injectables contain both high- and low-molecular-weight HA. Without cross-linking agents, they utilize NAHYCO technology to create their unique gel. Its thermal cross-linking stimulates collagen and elastin production by the slow release of HA. 

Clinical studies have demonstrated Profhilo’s efficacy. A study article by Goltsova & Shemonaeva (2019) showed significant improvement in skin hydration and elasticity after treatment. The involved clinicians and subjects reported high satisfaction levels, indicating Profhilo’s effectiveness in addressing skin roughness and laxity.

Profhilo vs. Other HA-Based Treatments

Like other HA-based dermal fillers, Profhilo uses hyaluronic acid (HA) for skin rejuvenation. However, unlike traditional HA fillers, Profhilo does not show immediate results. Instead, this injectable offers gradual improvement, showing results from the skin’s deep layers.

Moreover, traditional HA fillers aim to fill wrinkles and restore volume, while Profhilo stimulates collagen and elastin production in the deep layers of the skin, working gradually over time. Additionally, medical professionals know how Profhilo injections integrate seamlessly into the skin, offering multiple benefits.

  • Stimulate Collagen and Elastin Production
  • Longer-Lasting Results
  • Enhances Skin Support and Improves Skin Hydration
  • Visible Skin Lift and Overall Skin Appearance
  • Smoother, Brighter Skin with Fewer Fine Lines

Unlike traditional HA fillers, Profhilo stimulates collagen and elastin production, improving skin quality. It’s not a filler but a bio-remodeling agent that enhances skin texture and reduces wrinkles.

 It’s administered using the BAP technique, injecting small amounts of product at strategic points.

The Safety and Efficacy of HA in Profhilo

A medical professional administering a facial injection to a patient.

It’s worth noting that medical professionals with comprehensive knowledge about the treatment, facial anatomy, and proper Profhilo injection depth and technique can lead to optimal treatment outcomes. Safety assessment data by Cassuto et al. (2020) revealed a deficient number of adverse events supporting Profhilo injections’ high tolerability and safety, had been reported. 

All the reported events were early-onset injection site reactions, none of which led to further or severe complications. All these events were resolved without complications, implying Profhilo’s favorable safety profile. Furthermore, a study by Sparavigna et al. (2024) showed that subjects marked a significant improvement in skin firmness and reduced superficial and deep wrinkles.

The study’s findings demonstrated Profhilo’s efficacy and tolerability as a bio-remodelling treatment. They also confirmed this product’s potential role in counteracting aging‐related alterations within the deep fat compartment of the face.

Medical professionals widely use HA in aesthetic medicine due to its biocompatibility, biodegradability, nontoxicity, and non-immunogenicity. Moreover, medical professionals utilize it in various medical aesthetic procedures, including dermal fillers and viscosupplementation, due to its ability to attract and maintain significant amounts of water.

Medical professionals must also know the proper indications for using Profhilo injections. The common areas include the face and neck, but they can also be used for the décolletage, hands, arms, knees, and abdomen.

Conclusion

Profhilo injections harness the power of hyaluronic acid (HA) to rejuvenate skin. Unlike traditional HA fillers, Profhilo focuses on gradual improvement of the skin quality rather than immediate volume. Its HA formulation stimulates collagen and elastin production, promoting skin firmness and hydration which makes it a promising choice for those seeking radiant, youthful skin. 

FAQs

1. What are the critical properties of hyaluronic acid (HA) in Profhilo?

HA in Profhilo helps retain moisture, improves skin hydration, and contributes to skin elasticity and firmness.

2. How does Profhilo differ from traditional HA fillers? 

Profhilo stimulates collagen and elastin production in the deep layers of the skin, offering longer-lasting results and gradual improvement.

3. What are the unique benefits of Profhilo injections?

Profhilo integrates seamlessly into the skin, stimulates collagen and elastin production, and enhances skin support and hydration.

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References

  1. Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253–258. https://doi.org/10.4161/derm.21923
  2. Sparavigna, A., Grimolizzi, F., Cigni, C., Lualdi, R., & Bellia, G. (2024). Efficacy and tolerability of Profhilo® Structura intended to restore lateral cheek fat compartment: An observational pilot study. Health science reports, 7(1), e1743. https://doi.org/10.1002/hsr2.1743