A healthcare provider's stethoscope, medical syringes and vials, and medications.

According to WebMD, Synvisc One knee injections have received an average rating of 3.0 out of five stars based on 266 patient reviews. While these ratings reflect a range of patient experiences, they also highlight Synvisc One as a viable treatment option for those with knee osteoarthritis (OA).

Knee osteoarthritis (OA) presents with progressively intensifying symptoms. As these symptoms escalate in individuals with early to moderate knee OA, the search for effective treatments gains urgency. Amidst many brand-name products, Synvisc One offers a single-injection therapy specifically designed for knee OA patients.

This article will explore Synvisc One pros and cons, the injection treatment, and factors that make it a suitable candidate for the procedure.

Key Takeaways

  • Synvisc One supplements the joint’s synovial fluid with the lost hyaluronic acid (HA), acting as a lubricant and shock absorber when injected into the affected knee joint.
  • Synvisc One offers various advantages, such as pain relief, long-lasting treatment outcomes, and minimal side effects.
  • While Synvisc One can offer various advantages for treating knee osteoarthritis, understanding and considering its cons can help individuals make informed healthcare decisions.
  • Synvisc One is typically considered and indicated for individuals with knee OA who have not received significant relief from conservative therapies or simple analgesics. 
  • Counseling and discussing the benefits and potential risks can help individuals understand their Synvisc One injection treatment.

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Pros of Synvisc One

The packaging of Synvisc One at Medica Depot.

Synvisc One is one of the known injection treatments for its effectiveness in most cases. Like other viscosupplements, Synvisc One supplements the joint’s synovial fluid with the lost hyaluronic acid (HA). It effectively lubricates and cushions the joints to reduce friction and alleviate pain when moving.

  • Effective Pain Relief: The joint’s synovial fluid primarily capitalizes on HA. Synvisc One replenishes the lost HA in the synovial fluid, acting as a lubricant and shock absorber for the joints. When properly injected into the affected joints, Synvisc One helps reduce pain and improve joint function, which the symptoms of knee osteoarthritis cause.
  • Long-Lasting Effects: Despite its single-injection therapy, Synvisc One can provide up to six (6) months of relief from OA symptoms. The duration of pain relief can vary from early to severe cases, wherein milder cases can receive longer results. Medical professionals may also recommend repeat treatments for individuals to maintain the symptomatic relief.
  • Minimal Side Effects: Patients can expect several common side effects, such as pain, swelling, heat, redness, and fluid build-up around the knee. Rare adverse events may also occur, and seeking medical attention when these persist is essential.
  • Arthralgia
  • Arthritis
  • Arthropathy
  • Injection site pain
  • Joint effusion

Cons of Synvisc One

An individual suffering from knee pain while exercising.

While Synvisc One can offer significant advantages for treating knee osteoarthritis, understanding and considering its cons can help individuals make informed healthcare decisions. Medical professionals must explain these factors to patients to build trust between the two parties.  

  • Temporary Discomfort: Patients may experience temporary side effects or discomfort after treatment. Pain, swelling, heat, redness, and fluid build-up around the knee are generally mild to moderate. Providers may recommend resting and icing the knee briefly after the injections. Moreover, patients should also avoid strenuous activities for the next 48 hours.
  • Limited Insurance Coverage: While Medicare and most insurance plans cover Synvisc One injections, not all insurers and plans may reimburse the procedure cost. The benefits of the specific plan that covers you may still vary. We highly recommend that patients check with their insurer before receiving Synvisc One knee injections.
  • Ineffectiveness in Severe Cases: Synvisc One has shown its effectiveness in addressing knee osteoarthritis (OA) concerns, providing symptomatic relief to patients. However, its efficacy may vary from one patient to another, particularly with the severity of their OA condition. Early to milder knee OA conditions can adapt better to the medicine in relieving symptoms, while severe cases may offer a shorter relief or inadequate effect.

So, is Synvisc a steroid? Synvisc One is a viscosupplement that capitalizes on hyaluronic acid, a substance almost similar to the healthy joint fluid. Both may offer injection therapies, but they differ in their composition and formulation.

Before undergoing treatment, patients should first consult their medical professionals to determine the most suitable therapy for their knee OA condition. It’s worth noting that Synvisc One or other viscosupplements are indicated when first-line therapies have not brought adequate relief to OA patients.

Patient Selection and Counseling

A doctor-patient counseling session.

Medical professionals play a significant role in Synvisc One injection treatment. Their expertise can help them align the injection’s benefits to the patient’s specific needs, desired goals, knee osteoarthritis (OA) condition, and overall health. Creating a tailored treatment plan for each patient ensures the maximum benefit of Synvisc One and minimizes potential risks and complications.

Synvisc One is typically considered and indicated for individuals with knee OA who have not received significant relief from conservative therapies or simple analgesics. If they have tried these options and still experience OA symptoms, medical professionals may suggest Synvisc One as a suitable treatment.

The US Food and Drug Administration has approved this treatment for patients who have not experienced relief from first-line therapies. According to the Synvisc prescribing information, specific conditions may prevent an individual from receiving Synvisc One. Understanding these warnings can prevent patients from further complications.

  • Do not administer Synvisc One to patients with an infected knee joint, skin disease, or infection around the injection site.
  • Do not administer Synvisc One to patients with known allergies to the product or hyaluronan-based products.

After learning about patient selection, it’s essential to undergo counseling as a crucial part of pharmaceutical care. This can help influence patient behavior, adherence, and decision-making. Discussing the benefits and potential risks can help individuals understand their Synvisc One injection treatment. Other discussions in counseling may include:

  • Treatment Procedure
  • Financial Implications
  • Treatment Maintenance
  • Realistic Expectations

Medical professionals must effectively manage patients’ expectations to ensure their satisfaction with the Synvisc One process and outcomes. Patients should understand that Synvisc One offers a single-injection therapy, requiring intra-articular, direct administration into the affected knee joint.

Moreover, providers may highly recommend individuals avoid strenuous activities for approximately 48 hours after injection. They may also suggest applying ice briefly to prevent pain or swelling in the injection site after treatment.

Patients can also expect pain relief a few weeks after the injection treatment, which can last for up to six (6) months, depending on the severity of the OA condition. Milder cases may experience a longer duration of symptomatic relief.

Conclusion

Synvisc One offers a promising solution for knee osteoarthritis (OA) patients. Its benefits include effective pain relief, long-lasting effects, and minimal side effects. It works by supplementing the synovial fluid in the knee to help lubricate and cushion the joint. The effect duration can typically last up to six (6) months.

However, Synvisc One has certain drawbacks, such as temporary discomfort, limited insurance coverage, and potential ineffectiveness in severe cases. Hence, patient selection and counseling are crucial for patients to understand these factors and manage their expectations. This can also ensure patient satisfaction with the treatment procedure and results.

FAQs

1. What is Synvisc One?

Synvisc One is a single-injection therapy designed for individuals suffering from pain associated with knee osteoarthritis (OA).

2. What are the pros of Synvisc One?

Some critical advantages of Synvisc One include effective pain relief, long-lasting effects, and minimal side effects. Medical professionals should discuss these factors to efficiently answer patients’ questions about the treatment.

3. What are the cons of Synvisc One?

Some disadvantages of Synvisc One include temporary discomfort, limited insurance coverage, and ineffectiveness in severe cases. Understanding these can help individuals make informed healthcare decisions.

4. Who is a suitable candidate for Synvisc One treatment?

Individuals with knee OA who have not received significant relief from conservative therapies or simple analgesics may be suitable candidates for Synvisc One treatment. Medical professionals can help determine if this is an appropriate treatment option.

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References

  1. User Reviews for Synvisc-One Intra-Articular. (n.d.). Reviews.webmd.com. Retrieved April 25, 2024, from https://reviews.webmd.com/drugs/drugreview-151941-synvisc-one-intra-articular
  2. Frequently Asked Questions | Synvisc-One® Official Site. (n.d.). Synvisc One. https://www.synviscone.com/what-is-synvisc-one/synvisc-one-faqs