The 2019 Global Burden of Disease study shed light on osteoarthritis, a prevalent degenerative joint disease worldwide. The study found that 73% of those affected were 55 or older. Females represent 60% among this age group, underscoring the disease’s significant impact on this demographic.
Osteoarthritis (OA) often hinders individuals’ daily activities. Despite its incurable nature, a non-surgical treatment option exists in the form of Euflexxa. This three-injection therapy provides temporary yet long-lasting relief from OA symptoms, enabling patients to improve their joint functionality and overall quality of life.
In this article, we will delve into the Euflexxa treatment, its potential side effects, and the three-injection therapy’s safety and efficacy.
Key Takeaways
- Euflexxa injection works in two ways after the treatment: lubrication and cushioning and reducing inflammation and pain.
- According to Euflexxa-treated patients, pain relief can begin as early as a week after the first injection and continues to improve until the last session.
- These common side effects do not typically last for a long time and may occur right after Euflexxa injections.
- Once individuals feel bothersome about these symptoms, they should visit their medical practitioners to seek medical attention and avoid the condition worsening.
- Medical practitioners must educate the patients about the importance of adhering to the treatment schedule and strictly following the provider’s instructions to achieve a safe and effective treatment.
- Providers should inform patients about the potential risks or the long-term side effects after the treatment.
What is Euflexxa and How Does it Work?
Euflexxa offers a minimally invasive solution for individuals suffering from osteoarthritis and its symptoms. Osteoarthritis is a degenerative joint disease characterized by joint pain, stiffness, and swelling in the joints. Euflexxa mainly contains hyaluronic acid to allow pain-free joint movement.
This hyaluronic acid medicine is a substance similar to the fluid that naturally surrounds the joints. The synovial fluid in the joints is primarily composed of hyaluronic acid to act as a lubricant and shock absorber for the joints. Medical professionals specifically use Euflexxa for the knee joint to address the OA symptoms.
Aside from the HA component, Euflexxa has various ingredients for each injection. These ingredients have specific properties that offer different benefits in the formulation of the injection:
- Sodium Hyaluronate
- Sodium Chloride
- Disodium Hydrogen Phosphate Dodecahydrate
- Sodium Dihydrogen Phosphate Dihydrate
Medical professionals must administer these injections to the patients to ensure the safety and efficacy of the entire treatment. They know the best injection technique to directly inject the solution into the knee joint and offer a long-lasting solution for OA patients.
So, how much Euflexxa dosage does medical professionals need? They may administer 1 mL or 2 mL of Euflexxa in every injection session of the patients. This injection works in two ways after the treatment: lubrication and cushioning and reducing inflammation and pain.
Euflexxa can help OA patients reduce friction during movement, help with shock absorption, and protect the cartilage. The formulation of this injection closely resembles the natural HA found in the knee and other joints.
So, how long does the injection treatment last? The three-injection therapy can offer a relief effect for up to six (6) months. According to Euflexxa-treated patients, pain relief can begin as early as a week after the first injection and continues to improve until the last session.
Common Serious Side Effects of Euflexxa
Like other medical or aesthetic treatments, medical practitioners should discuss the potential Euflexxa long term side effects and if those would persist for quite some time. It’s necessary to understand the typical adverse reactions reported in clinical trials.
- Joint Pain
- Back Pain
- Limb Pain
- Muscle Pain
- Joint Swelling
These side effects do not typically last for a long time and may occur right after Euflexxa injections. Most adverse effects resolve as the body adjusts to the HA treatment. These side effects are generally mild to moderate and can dissipate after quite a while.
However, if a side effect persist longer than the doctor’s advice, it’s best to consult or visit them to get prompt medical attention. Individuals may not experience all prolonged side effects at once, as influencing factors may also lead to their occurrence.
- Individual Sensitivity
- Injection Technique
- Patient Health
Rare Long-Term Side Effects of Euflexxa and Drug Interactions
While side effects typically range from mild to moderate, a small percentage remains for rare and severe side effects. Due to its rare occurrences, these side effects are faced in minimal reported cases.
- Hypersensitivity: Anaphylaxis or anaphylactoid reaction
- Gastrointestinal Effects: Nausea, vomiting, abdominal pain, or diarrhea
- Cardiovascular Considerations: Low blood pressure
- Musculoskeletal Reactions: Arthralgia or joint pain, back pain, leg discomfort, or leg pain
- Respiratory Symptoms: Upper respiratory tract infection, sinusitis, bronchitis, or rhinitis
Similar to the common side effects, several factors may also influence the occurrence of side effects. Once individuals feel bothersome about these symptoms, they should visit their medical practitioners to seek medical attention and avoid the condition worsening.
- Individual Sensitivity: Some patients may have allergic reactions to sodium hyaluronate that may cause a few effects, such as hives, breathing difficulty, or swelling of other body parts.
- Injection Technique: Medical professionals know that an aseptic technique should be used in administering these injections. When they use an improper injection technique, complications may arise.
- Patient Health: The overall health of the patient can influence the occurrence and severity of these various side effects of Euflexxa.
- Current Medications: Other concurrent medications may also affect the Euflexxa injection and can potentially increase the risk of risks.
- Dosage and Frequency: These factors also play a role in the development of side effects.
Managing Long-Term Side Effects of Euflexxa
In monitoring and addressing common or serious side effects, patients should be in contact with their trusted medical practitioners to watch the changes, especially around the injection site. Regular follow-ups with the providers can also help in monitoring the patient’s condition after the treatment.
Patients may ask their healthcare providers how to manage the expected and temporary side effects. They may allow over-the-counter pain relievers or ice packs to manage the pain, swelling and other non serious afflictions of the affected site. Patients must report any persistent or worsening side effects of the drug immediately to their healthcare professional.
Medical professionals should also discuss the protocols for identifying and managing rare side effects in patients and dispense medical advice about the drug. This can help them gain awareness and would allow them to seek medical attention promptly. They should understand that these side effects may be inevitable after treatment.
These experts should inform the patients to tell them when symptoms like severe pain or swelling, skin rash, itching, stuffy nose, tightness in the chest, etc., occur. They should know all the potential side effects, including the common and rare symptoms that may occur after the injection.
Medical experts should also advise patients to report unusual or bothersome symptoms to avoid worsening. Moreover, they must educate the patients about the importance of adhering to the treatment schedule and strictly following the provider’s instructions to achieve a safe and effective treatment.
Persistence of Side Effects Over Time
With Euflexxa deemed safe for repeated treatment after six months, the persistence of side effects over time may happen. After injections, individuals may deal with various side effects, and these may vary among patients.
- Common Side Effects: These symptoms include joint pain, back pain, limb pain, muscle pain, and joint swelling. These side effects may usually resolve as the body adjusts to the treatment, temporarily lasting for a few weeks.
- Rare Side Effects: Hypersensitivity reactions or musculoskeletal effects may take longer to resolve and most likely require medical attention.
Persistent side effects can influence patient outcomes and their satisfaction regarding the injection treatment. Severe or long-lasting side effects may expect a discontinuation of the Euflexxa therapy. It’s worth noting that most patients do not experience severe or long-term side effects. The Euflexxa’s benefits often outweigh the potential side effects.
If worrisome symptoms occur or side effects persist quite a while after the treatment, consult your medical practitioners for an alternative treatment for osteoarthritis. Patients should adhere to consistent regular follow-ups for healthcare providers to monitor their condition, including the side effects and benefits of the Euflexxa injections.
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Conclusion
Medical professionals may recommend Euflexxa’s three-injection therapy for individuals who have not responded to any medications or therapies for osteoarthritis. While deemed safe and effective, providers should inform patients about the potential risks or Euflexxa’s long-term side effects after the treatment. This can help patients make informed healthcare decisions for themselves.
Common side effects may resolve after a few weeks, while rare symptoms need prompt medical attention. Euflexxa patients should follow their providers’ instructions for post-treatment. Moreover, a consultation to create a tailored treatment plan can help achieve safe and effective treatment and optimal outcomes without compromising the patient’s overall health.
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References
- Institute for Health Metrics and Evaluation. (2019). GBD 2019: Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Institute for Health Metrics and Evaluation; University of Washington. https://vizhub.healthdata.org/gbd-results/
- SUMMARY OF SAFETY AND EFFECTIVENESS DATA (SSED). (n.d.). Retrieved April 1, 2024, from https://www.accessdata.fda.gov/cdrh_docs/pdf/P010029S008b.pdf
