What does this product come with?

Each package contains: 3-2ml prefilled syringes; And 1 package insert.

How does this product work?

Osteoarthritis is characterized by the breakdown of hyaluronic acid in the joints’ synovial fluid. Known for the lubrication and cushioning of the joints, this substance causes the bones in the joints to rub together as it diminishes. As this occurs, pain, inflammation, and decreased mobility are experienced, severely affecting the patient’s overall quality of life. When injected into the joints, <a href="https://www.mdpt2.forgahosting.com/synvisc-1.html">Synvisc</a> replaces this lost hyaluronic acid and cushions the joints to prevent bones from rubbing together. This reduces inflammation and pain, offering much-wanted relief. With this, Synvisc may also help delay knee or other osteoarthritis-related surgeries, allowing your clients to continue with life as usual.

SYNVISC®

Brand: SYNVISC®

$329

Save at least $283 on this product when buying at Medica Depot*

*Compared to the average local price in your country based on market data.

Quantity	Price
1 - 5	$329.00
6 - 10	$319.00
11 - 20	$314.00
21+	$309.00

5.00

(4)

Manufacturer: Sanofi Genzyme
Active Substance(s): HYLAN GF 20
Strength: 2ml (16mg) Hylan G-F 20
Package Size: 3 x 2ml Pre-Filled Syringes
Accessories: Package insert

Synvisc® (hylan G-F 20) is a viscosupplement injection that supplements the fluid in your knee to help lubricate and cushion the joint. Synvisc is a sterile high molecular weight fluid, which contains Hylan A fluid, Hylan B gel and salt water designed to treat osteoarthritis pain in the knee, hip, ankle or shoulder. The treatment works by restoring the elasticity and viscosity within the joint allowing a more extensive movement of the joint. Synvisc® can be used as a temporary replacement and supplement for synovial fluid for patients with osteoarthritis, who have failed to respond to a more conservative therapy, such as non-drug treatment options.Osteoarthritis treatment that contains hylan, a natural found in the synovial fluid of the joints.

SYNVISC is a gel-like mixture that is made up of hylan A fluid, hylan B gel, and salt water. Hylan A and hylan B are made from a substance called hyaluronan (pronounced hy-al-u-ROE-nan), also known as sodium hyaluronate that comes from chicken combs. Hyaluronan is a natural substance found in the body aand is present in very high amounts in joints. The body’s own hyaluronan acts like a lubricant and a shock absorber in the joint and is needed for the joint to work properly. Osteoarthritis (pronounced os-TE-o-ar-THRI-tis) (OA) is a type of arthritis that involves the wearing down of cartilage (the protective covering on the ends of your bones). In OA, there may not be enough hyaluronan, and there may be a decrease in the quality of the hyaluronan in the joint. SYNVISC comes in syringes containing 2 mL (half a teaspoon) of product. SYNVISC is injected directly into your knee.

SYNVISC is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics, e.g., acetaminophen.

Synvisc (hylan G-F 20) is a sterile, nonpyrogenic, elastoviscous fluid containing hylans. Hylans are derivatives of hyaluronan (sodium salt of hyaluronic acid) and consist of repeating disaccharide units of N-acetylglucosamine and sodium glucuronate. Hylan A has an average molecular weight of approximately 6,000,000 daltons and hylan B is a hydrated gel. Hylan G-F 20 contains hylan A and hylan B (8.0 mg ± 2.0 mg per ml) in buffered physiological sodium chloride solution (pH 7.2 ± 0.3).

Contraindications

Do not administer to patients with known hypersensitivity (allergy) to hyaluronan (sodium hyaluronate) preparations.
Do not inject SYNVISC in the knees of patients having knee joint infections or skin diseases or infections in the area of the injection site.

After-care

Avoid activities that put excessive strain on your knee, such as jogging, lifting, or prolonged standing for 48 hours following the injection. Please consult your doctor regarding the appropriate time to resume such activities.
If you have any mild pain or swelling at the injection site, apply an ice pack on your knee as recommended by your doctor.
The most common side effects seen with the SYNVISC® family are pain, swelling, heat, redness, and fluid buildup around the knee. Please consult your doctor if you have concerns, if your symptoms do not go away, and/or if you have other side effects.

Frequently Asked Questions

Medical practitioners may purchzse Synvisc online at low wholesale pricing from Medica Depot.

Each package contains:

3-2ml prefilled syringes;
And 1 package insert.

Synvisc’s chemically cross-linked formula makes it more stable than other viscosupplements. This means that it may provide clients great relief from their osteoarthritis symptoms for up to 6 months.

Osteoarthritis is characterized by the breakdown of hyaluronic acid in the joints’ synovial fluid. Known for the lubrication and cushioning of the joints, this substance causes the bones in the joints to rub together as it diminishes. As this occurs, pain, inflammation, and decreased mobility are experienced, severely affecting the patient’s overall quality of life.

When injected into the joints, Synvisc replaces this lost hyaluronic acid and cushions the joints to prevent bones from rubbing together. This reduces inflammation and pain, offering much-wanted relief. With this, Synvisc may also help delay knee or other osteoarthritis-related surgeries, allowing your clients to continue with life as usual.

Synvisc is comprised of hylan (8mg/milliliter), sodium chloride (8.5mg/milliliter), disodium hydrogen phosphate (0.16mg/milliliter), and sodium dihydrogen phosphate hydrate (0.04mg/milliliter).

Synvisc is intended for intra-articular use by a licensed physician to treat pain associated with osteoarthritis of the knees, hips, ankles, or shoulders. Inject at room temperature with an 18–22G needle using strict aseptic procedures. For more guidance on the injection process, please consult the included product pamphlet.

The typical course of this procedure varies according to the area being treated. For the treatment of osteoarthritis of the knee, it is recommended to administer 3-2 milliliter injections, 1 week apart. The maximum recommended dosage is 6 injections within 6 months, with a minimum of 4 weeks between treatment regimens. To treat the hips, ankles or shoulders, it is recommended to start with 1-2 milliliter injection, only administering a second injection if symptomatic relief from the initial session is inadequate.

Synvisc is intended for the treatment of osteoarthritis of the knees, hips, ankles, and shoulders.

Prospective clinical data in knee osteoarthritis patients have shown this treatment to last up to 52 weeks following a single course of 3 Synvisc injections; however, the manufacturer specifies the results last up to 6 months.

Clients often turn to Synvisc to replace or to complement other osteoarthritis treatments, like anti-inflammatory medications and physical therapy. Clients may also choose Synvisc treatments to put off surgery until a later date. Synvisc injections can help your clients whether they are experiencing their first osteoarthritis symptoms, or are in advanced stages of this ailment. Synvisc not only eases your patient’s pain, but can also mean increased mobility and quality of life.

If your clients are allergic to birds or to eggs, they should not undergo this treatment, as Synvisc’s formula is derived from rooster combs. It is unknown how Synvisc may affect developing children, so clients who are pregnant, nursing, or under the age of 18 should not use Synvisc.

Synvisc has been used in the US since 1997, when it gained FDA approval. Over the years, Synvisc has become 1 of the most commonly used treatments for osteoarthritis sufferers. Both orthopedic doctors and their patients trust Synvisc to provide effective relief from osteoarthritis inflammation and pain.

Purchasing Synvisc to treat your patients is an effective way to not only bring them immediate relief, but also to prevent future damage. With this treatment, you can effectively halt the progression of your patients’ osteoarthritis, reducing their need for further surgeries.

With the aging baby boomer population, osteoarthritis is on rise. You should be prepared to treat this issue with plenty of Synvisc on hand at your office or clinic.

Despite being similar to the hyaluronic acid found within the body, Synvisc may cause certain side effects. Commonly, these include swelling, pain, or irritation at the injection site. In order to lower the risk of allergic reactions, patients with known avian allergies should not proceed with this treatment.